What is Glucosamine?
Glucosamine is made in the body from fructose and the amino acid glutamine. It is also produced from the exoskeleton of shellfish or by the fermentation of grains such as wheat or corn. This protein helps your body build cartilage around your bones, near the joints and keeps it lubricated for better movement and flexibility. Cartilage is the flexible connective tissue that protects and cushions the bones and keeps them from rubbing against each other.
What is Chondroitin?
Chondroitin sulfate is a natural compound found in the body as part of the tissue that cushions the joints. Chondroitin sulfate can be found in certain animal-based foods such as bone broths or stews. It is believed to help the body maintain fluid and flexibility. Studies suggest that it may slow cartilage breakdown and may also help in stimulating cartilage growth.
What is Methylsulfonymethane (“MSM”)?
Methylsulfonymethane (“MSM”) is an organic sulfur found in fruits, vegetables, grains, and milk. It helps support muscles and tendons in the body. It has been known to improve joint pain and swelling. It has anti-inflammatory and antioxidant effects. The major component of MSM is sulfur and this sulfur plays a key role in the creation of collagen. It also aids in the production of immunoglobulins which help the immune system.
What are the Benefits of Glucosamine and Chondroitin with MSM?
Glucosamine and Chondroitin are herbal supplements, when combined, are used to manage pain from arthritis. On occasion, MSM is added as an additional supplement. Glucosamine and Chondroitin play a part in joint health and MSM has anti-inflammatory benefits.
In addition, Glucosamine and Chondroitin are used in veterinary medicine to treat osteoarthritis.
Who should use Glucosamine Chondroitin MSM?
People with arthritis, especially those with osteoarthritis, could benefit from using Glucosamine Chondroitin with MSM. As people get older, the cartilage breaks down and becomes less flexible. When this happens, it leads to joint deterioration, pain, inflammation, and tissue damage. The painful symptoms of osteoarthritis appear when the cartilage wears down, and the bare bones begin to rub together.
Although these supplements are tolerated well, there can be some side effects. The most common are nausea, diarrhea/constipation, heartburn, increased intestinal gas, skin rash, headache, and fatigue.
Cautions and Warnings
Before taking any supplement, you should consult with your healthcare provider to make sure it is safe to use. Do not take this product if you are on blood thinners (Warfarin) or cancer medications (doxorubicin, Etoposide). You should not take this product if you have diabetes because it may raise sugar levels in your blood. Do not exceed recommended dose. Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before using this. This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish, and crustacean shellfish. Keep out of reach of children. Do not use if safety seal is damaged or missing. Store in a cool, dry place.
These comments have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
References for More Information
 Jerosch, Jorg. “Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids.” International Journal of Rheumatology. August 2, 2011. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150191/
 Bhathal, Angel; Spryszak, Meredith; Louizos, Christopher; and Frankel, Grace. “Glucosamine and Chondroitin Use in Canines for Osteoarthritis: A Review.” Open Veterinary Journal. February 24, 2017. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356289/